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curently ongoing...

Research Projects

Epigenetics

MAGE - A Model of the Aging Epigenome
Epigenetic inheritance
Properties of histone modifications
Epigenetic Memory
Evolution of epigenetic regulation in beetles (Coleoptera)

Evolution of Life

The modern RNA world: non-coding RNA-based genetic regulation as a prerequisite for the emergence of multicellular complexity (funded by the National Council of Science and Technology in Mexico
Differential evolution of non-coding DNA across eukaryotes could lead towards different pathways of multicellular complexity (funded by the Max Planck Institute for Mathematics in the Sciences
Investigation of the gene phylogeny of GPCRs and associated molecules

RNA-Protein Interaction

Inference and structural analysis of RNA-protein binding motifs
Evolution of Complex Translational Control Elements in the Innate Immune Response
Unusual RNA-polymerases: reaction mechanism and substrate specificity of tRNA nucleotidyltransferases

Who do we work with?

Our Working Groups